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Palmitate-induced Regulation of PPARγ via PGC1α: a Mechanism for Lipid Accumulation in the Liver in Nonalcoholic Fatty Liver Disease

The aim was to examine the effect of free fatty acids on the regulation of PPARγ-PGC1α pathway, and the effect of PPARγ/PGC1α in NAFLD. The mRNA and protein expression of PGC1α and phospho/total PPARγ were examined in Huh7 cells after the palmitate/oleate treatment with/without the transfection with...

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Dades bibliogràfiques
Publicat a:Int J Med Sci
Autors principals: Maruyama, Hitoshi, Kiyono, Soichiro, Kondo, Takayuki, Sekimoto, Tadashi, Yokosuka, Osamu
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773281/
https://ncbi.nlm.nih.gov/pubmed/26941577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.13581
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