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Reconstructing Causal Biological Networks through Active Learning

Reverse-engineering of biological networks is a central problem in systems biology. The use of intervention data, such as gene knockouts or knockdowns, is typically used for teasing apart causal relationships among genes. Under time or resource constraints, one needs to carefully choose which interv...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cho, Hyunghoon, Berger, Bonnie, Peng, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773135/
https://ncbi.nlm.nih.gov/pubmed/26930205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150611
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