Placental epigenetic patterning of glucocorticoid response genes is associated with infant neurodevelopment

AIM: To determine associations between methylation of NR3C1, HSD11B2, FKBP5 and ADCYAP1R1 and newborn neurobehavioral outcomes. METHODS: In 537 newborns, placental methylation was quantified using bisulfite pyrosequencing. Profiles of neurobehavior were derived via the Neonatal Intensive Care Unit N...

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Библиографические подробности
Опубликовано в: :Epigenomics
Главные авторы: Paquette, Alison G, Lester, Barry M, Lesseur, Corina, Armstrong, David A, Guerin, Dylan J, Appleton, Allison A, Marsit, Carmen J
Формат: Artigo
Язык:Inglês
Опубликовано: Future Medicine Ltd 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772971/
https://ncbi.nlm.nih.gov/pubmed/26343289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.15.28
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