Reduction in mitochondrial iron alleviates cardiac damage during injury

Excess cellular iron increases reactive oxygen species (ROS) production and causes cellular damage. Mitochondria are the major site of iron metabolism and ROS production; however, few studies have investigated the role of mitochondrial iron in the development of cardiac disorders, such as ischemic h...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Chang, Hsiang‐Chun, Wu, Rongxue, Shang, Meng, Sato, Tatsuya, Chen, Chunlei, Shapiro, Jason S, Liu, Ting, Thakur, Anita, Sawicki, Konrad T, Prasad, Sathyamangla VN, Ardehali, Hossein
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772952/
https://ncbi.nlm.nih.gov/pubmed/26896449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505748
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