Quetiapine Ameliorates Schizophrenia-Like Behaviors and Protects Myelin Integrity in Cuprizone Intoxicated Mice: The Involvement of Notch Signaling Pathway

BACKGROUND: White matter disturbances and myelin impairment are key features of schizophrenia. The antipsychotic drug quetiapine can promote the maturation of oligodendrocytes, but the molecular mechanisms remain largely unknown. METHODS: The schizophrenia-like behaviors, degrees of demyelination, a...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Wang, Hua-ning, Liu, Gao-hua, Zhang, Rui-guo, Xue, Fen, Wu, Di, Chen, Yun-chun, Peng, Ye, Peng, Zheng-wu, Tan, Qing-rong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772821/
https://ncbi.nlm.nih.gov/pubmed/26232790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv088
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