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A 4.5-megabase yeast artificial chromosome contig from human chromosome 13q14.3 ordering 9 polymorphic microsatellites (22 sequence-tagged sites) tightly linked to the Wilson disease locus.

We have previously performed a genetic analysis of multiply affected families to map a locus responsible for Wilson disease (WND) to a 0.3-centimorgan (cM) region within chromosome 13q14.3, between D13S31 and D13S59. Here we describe the construction of a contig of approximately 4.5 Mb, which spans...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: White, A, Tomfohrde, J, Stewart, E, Barnes, R, Le Paslier, D, Weissenbach, J, Cavalli-Sforza, L, Farrer, L, Bowcock, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8234264/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.21.10105
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