Visualization of complex DNA double-strand breaks in a tumor treated with carbon ion radiotherapy

Carbon ion radiotherapy shows great potential as a cure for X-ray-resistant tumors. Basic research suggests that the strong cell-killing effect induced by carbon ions is based on their ability to cause complex DNA double-strand breaks (DSBs). However, evidence supporting the formation of complex DSB...

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Udgivet i:Sci Rep
Main Authors: Oike, Takahiro, Niimi, Atsuko, Okonogi, Noriyuki, Murata, Kazutoshi, Matsumura, Akihiko, Noda, Shin-Ei, Kobayashi, Daijiro, Iwanaga, Mototaro, Tsuchida, Keisuke, Kanai, Tatsuaki, Ohno, Tatsuya, Shibata, Atsushi, Nakano, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772097/
https://ncbi.nlm.nih.gov/pubmed/26925533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22275
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