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The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis

The mitochondrial translocator protein (TSPO) has been implicated in CNS diseases. Here, we sought to determine the specific role of TSPO in experimental autoimmune encephalomyelitis (EAE), the most studied animal model of multiple sclerosis (MS). To fundamentally elucidate the functions of TSPO, we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Daugherty, Daniel J., Chechneva, Olga, Mayrhofer, Florian, Deng, Wenbin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772008/
https://ncbi.nlm.nih.gov/pubmed/26925573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22556
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