Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus—the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial

OBJECTIVE: To assess the effect of metformin versus placebo both in combination with insulin analogue treatment on changes in carotid intima-media thickness (IMT) in patients with type 2 diabetes. DESIGN AND SETTING: Investigator-initiated, randomised, placebo-controlled trial with a 2×3 factorial d...

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Détails bibliographiques
Publié dans:BMJ Open
Auteurs principaux: Lundby-Christensen, Louise, Tarnow, Lise, Boesgaard, Trine W, S Lund, Søren, Wiinberg, Niels, Perrild, Hans, Krarup, Thure, Snorgaard, Ole, Gade-Rasmussen, Birthe, Thorsteinsson, Birger, Røder, Michael, Mathiesen, Elisabeth R, Jensen, Tonny, Vestergaard, Henrik, Hedetoft, Christoffer, Breum, Leif, Duun, Elsebeth, Sneppen, Simone B, Pedersen, Oluf, Hemmingsen, Bianca, Carstensen, Bendix, Madsbad, Sten, Gluud, Christian, Wetterslev, Jørn, Vaag, Allan, Almdal, Thomas P
Format: Artigo
Langue:Inglês
Publié: BMJ Publishing Group 2016
Sujets:
Diabetes and Endocrinology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771973/
https://ncbi.nlm.nih.gov/pubmed/26916684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008376
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