A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses

Early, presymptomatic intervention with oseltamivir (corresponding to the onset of a published host-based genomic signature of influenza infection) resulted in decreased overall influenza symptoms (aggregate symptom scores of 23.5 vs 46.3), more rapid resolution of clinical disease (20 hours earlier...

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Veröffentlicht in:Open Forum Infect Dis
Hauptverfasser: McClain, Micah T., Nicholson, Bradly P., Park, Lawrence P., Liu, Tzu-Yu, Hero, Alfred O., Tsalik, Ephraim L., Zaas, Aimee K., Veldman, Timothy, Hudson, Lori L., Lambkin-Williams, Robert, Gilbert, Anthony, Burke, Thomas, Nichols, Marshall, Ginsburg, Geoffrey S., Woods, Christopher W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771939/
https://ncbi.nlm.nih.gov/pubmed/26933666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofw007
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