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Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells

In the process of translation, ribosomes first assemble on mRNAs (translation initiation) and then translate along the mRNA (elongation) to synthesize proteins. Elongation pausing is deemed highly relevant to co-translational folding of nascent peptides and the functionality of protein products, whi...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Lian, Xinlei, Guo, Jiahui, Gu, Wei, Cui, Yizhi, Zhong, Jiayong, Jin, Jingjie, He, Qing-Yu, Wang, Tong, Zhang, Gong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771717/
https://ncbi.nlm.nih.gov/pubmed/26926465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005901
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