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Oligomers of Heat-Shock Proteins: Structures That Don’t Imply Function

Most proteins must remain soluble in the cytosol in order to perform their biological functions. To protect against undesired protein aggregation, living cells maintain a population of molecular chaperones that ensure the solubility of the proteome. Here we report simulations of a lattice model of i...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Jacobs, William M., Knowles, Tuomas P. J., Frenkel, Daan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771702/
https://ncbi.nlm.nih.gov/pubmed/26928170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004756
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