Increasing the Number of SNP loci does not Necessarily Improve Prediction Power at Least in the Comparison of MTHFR SNP and Haplotypes

BACKGROUND: Rapid advances in genotyping technology have made it possible to easily utilize a large number of genetic markers. According to information theory, an increase in the number of markers provides more information; however, the clinical usefulness does not increase linearly. This study aime...

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Détails bibliographiques
Publié dans:J Epidemiol
Auteurs principaux: Miyaki, Koichi, Takahashi, Yoshimitsu, Song, Yixuan, Zhang, Ling, Muramatsu, Masaaki, Nakayama, Takeo
Format: Artigo
Langue:Inglês
Publié: Japan Epidemiological Association 2008
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771609/
https://ncbi.nlm.nih.gov/pubmed/19075497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2188/jea.JE2008022
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