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Therapeutic Role of Interleukin 22 in Experimental Intra-abdominal Klebsiella pneumoniae Infection in Mice

Interleukin 22 (IL-22) is an IL-10-related cytokine produced by T helper 17 (Th17) cells and other immune cells that signals via IL-22 receptor alpha 1 (IL-22Ra1), which is expressed on epithelial tissues, as well as hepatocytes. IL-22 has been shown to have hepatoprotective effects that are mediate...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Zheng, Mingquan, Horne, William, McAleer, Jeremy P., Pociask, Derek, Eddens, Taylor, Good, Misty, Gao, Bin, Kolls, Jay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771339/
https://ncbi.nlm.nih.gov/pubmed/26729763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01268-15
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