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Overexpression of uncoupling protein 2 inhibits the high glucose-induced apoptosis of human umbilical vein endothelial cells

Ectopic apoptosis of vascular cells plays a critical role in the early stage development of diabetic retinopathy (DR). Uncoupling protein 2 (UCP2) is a mitochondrial modulator which protects against endothelial dysfunction. However, the role which UCP2 plays in endothelial apoptosis and its associat...

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Pubblicato in:Int J Mol Med
Autori principali: HE, YING, LUAN, ZHOU, FU, XUNAN, XU, XUN
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771113/
https://ncbi.nlm.nih.gov/pubmed/26846204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2478
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