Anti–IL-6 neutralizing antibody modulates blood-brain barrier function in the ovine fetus

Impaired blood-brain barrier function represents an important component of hypoxic-ischemic brain injury in the perinatal period. Proinflammatory cytokines could contribute to ischemia-related blood-brain barrier dysfunction. IL-6 increases vascular endothelial cell monolayer permeability in vitro....

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Bibliographic Details
Published in:FASEB J
Main Authors: Zhang, Jiyong, Sadowska, Grazyna B., Chen, Xiaodi, Park, Seon Yeong, Kim, Jeong-Eun, Bodge, Courtney A., Cummings, Erin, Lim, Yow-Pin, Makeyev, Oleksandr, Besio, Walter G., Gaitanis, John, Banks, William A., Stonestreet, Barbara S.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2015
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4771067/
https://ncbi.nlm.nih.gov/pubmed/25609424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-258822
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