Immune history profoundly affects broadly protective B cell responses to influenza

Generating a broadly protective influenza vaccine is critical to global health. Understanding how immune memory influences influenza immunity is central to this goal. We undertook an in-depth study of the B cell response to the pandemic 2009 H1N1 vaccine over consecutive years. Analysis of monoclona...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Andrews, Sarah F., Huang, Yunping, Kaur, Kaval, Popova, Lyubov I., Ho, Irvin Y., Pauli, Noel T., Dunand, Carole J. Henry, Taylor, William M, Lim, Samuel, Huang, Min, Qu, Xinyan, Lee, Jane-Hwei, Salgado-Ferrer, Marlene, Krammer, Florian, Palese, Peter, Wrammert, Jens, Ahmed, Rafi, Wilson, Patrick C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770855/
https://ncbi.nlm.nih.gov/pubmed/26631631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad0522
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