Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline

Cabergoline (CAB), the first-line drug for treatment of prolactinomas, is effective in suppressing prolactin hypersecretion, reducing tumor size, and restoring gonadal function. However, mechanisms for CAB-mediated tumor shrinkage are largely unknown. Here we report a novel cytotoxic mechanism for C...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Lin, Shao Jian, Leng, Zhi Gen, Guo, Yu Hang, Cai, Lin, Cai, Yu, Li, Ning, Shang, Han Bing, Le, Wei-Dong, Zhao, Wei Guo, Wu, Zhe Bao
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770775/
https://ncbi.nlm.nih.gov/pubmed/26513171
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