Bladder cancer cells re-educate TAMs through lactate shuttling in the microfluidic cancer microenvironment

BACKGROUND: In the present study, we aimed to investigate the influence of lactate shuttling on the functional polarization and spatial distribution of transitional cell carcinoma of the bladder (TCCB) cells and macrophages. METHODS: We designed a microfluidic coculture chip for real-time integrativ...

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Pubblicato in:Oncotarget
Autori principali: Zhao, Yang, Wang, Degui, Xu, Ting, Liu, Pengfei, Cao, Yanwei, Wang, Yonghua, Yang, Xuecheng, Xu, Xiaodong, Wang, Xinsheng, Niu, Haitao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770766/
https://ncbi.nlm.nih.gov/pubmed/26474279
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