Necrosis avid near infrared fluorescent cyanines for imaging cell death and their use to monitor therapeutic efficacy in mouse tumor models

Quantification of tumor necrosis in cancer patients is of diagnostic value as the amount of necrosis is correlated with disease prognosis and it could also be used to predict early efficacy of anti-cancer treatments. In the present study, we identified two near infrared fluorescent (NIRF) carboxylat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xie, Bangwen, Stammes, Marieke A., van Driel, Pieter B.A.A., Cruz, Luis J., Knol-Blankevoort, Vicky T., Löwik, Martijn A.M., Mezzanotte, Laura, Que, Ivo, Chan, Alan, van den Wijngaard, Jeroen P.H.M., Siebes, Maria, Gottschalk, Sven, Razansky, Daniel, Ntziachristos, Vasilis, Keereweer, Stijn, Horobin, Richard W., Hoehn, Mathias, Kaijzel, Eric L., van Beek, Ermond R., Snoeks, Thomas J.A., Löwik, Clemens W.G.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770755/
https://ncbi.nlm.nih.gov/pubmed/26472022
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