Necrosis avid near infrared fluorescent cyanines for imaging cell death and their use to monitor therapeutic efficacy in mouse tumor models

Quantification of tumor necrosis in cancer patients is of diagnostic value as the amount of necrosis is correlated with disease prognosis and it could also be used to predict early efficacy of anti-cancer treatments. In the present study, we identified two near infrared fluorescent (NIRF) carboxylat...

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Publicat a:Oncotarget
Autors principals: Xie, Bangwen, Stammes, Marieke A., van Driel, Pieter B.A.A., Cruz, Luis J., Knol-Blankevoort, Vicky T., Löwik, Martijn A.M., Mezzanotte, Laura, Que, Ivo, Chan, Alan, van den Wijngaard, Jeroen P.H.M., Siebes, Maria, Gottschalk, Sven, Razansky, Daniel, Ntziachristos, Vasilis, Keereweer, Stijn, Horobin, Richard W., Hoehn, Mathias, Kaijzel, Eric L., van Beek, Ermond R., Snoeks, Thomas J.A., Löwik, Clemens W.G.M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770755/
https://ncbi.nlm.nih.gov/pubmed/26472022
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