Interleukin-1 beta transactivates epidermal growth factor receptor via the CXCL1-CXCR2 axis in oral cancer

Hyperactivation of the epidermal growth factor receptor (EGFR) pathways and chronic inflammation are common characteristics of oral squamous cell carcinoma (OSCC). Previously, we reported that OSCC cells secrete interleukin-1 beta (IL-1β), which promotes the proliferation of the oral premalignant ce...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lee, Chia-Huei, Syu, Shih-Han, Liu, Ko-Jiunn, Chu, Pei-Yi, Yang, Wen-Chan, Lin, Pinpin, Shieh, Wan-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770743/
https://ncbi.nlm.nih.gov/pubmed/26462152
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