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UCP2 regulates mitochondrial fission and ventromedial nucleus control of glucose responsiveness

The ventromedial nucleus of the hypothalamus (VMH) plays a critical role in regulating systemic glucose homeostasis. How neurons in this brain area adapt to the changing metabolic environment to regulate circulating glucose levels is ill-defined. Here we show that glucose load results in mitochondri...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Toda, Chitoku, Kim, Jung Dae, Impellizzeri, Daniela, Cuzzocrea, Salvatore, Liu, Zhong-Wu, Diano, Sabrina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770556/
https://ncbi.nlm.nih.gov/pubmed/26919426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.02.010
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