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IL-18 contributes to susceptibility to Leishmania amazonensis infection by macrophage-independent mechanisms
We evaluated the role of IL-18 during Leishmania amazonensis infection in C57BL/6 mice, using IL-18KO mice. We showed that IL-18 is involved in susceptibility to L. amazonensis, since IL-18KO mice presented reduced lesions and parasite loads. Because macrophages are the host cells of the parasite, w...
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Publicado no: | Cytokine |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770538/ https://ncbi.nlm.nih.gov/pubmed/26009021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2015.01.021 |
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