Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep, and Emotional Processing in Humans

Lithium remains the gold standard in treating bipolar disorder but has unwanted toxicity and side effects. We previously reported that ebselen inhibits inositol monophosphatase (IMPase) and exhibits lithium-like effects in animal models through lowering of inositol. Ebselen has been tested in clinic...

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Sparad:
Bibliografiska uppgifter
I publikationen:Neuropsychopharmacology
Huvudupphovsmän: Singh, Nisha, Sharpley, Ann L, Emir, Uzay E, Masaki, Charles, Herzallah, Mohammad M, Gluck, Mark A, Sharp, Trevor, Harmer, Catherine J, Vasudevan, Sridhar R, Cowen, Philip J, Churchill, Grant C
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770517/
https://ncbi.nlm.nih.gov/pubmed/26593266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.343
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