Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep, and Emotional Processing in Humans

Lithium remains the gold standard in treating bipolar disorder but has unwanted toxicity and side effects. We previously reported that ebselen inhibits inositol monophosphatase (IMPase) and exhibits lithium-like effects in animal models through lowering of inositol. Ebselen has been tested in clinic...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Singh, Nisha, Sharpley, Ann L, Emir, Uzay E, Masaki, Charles, Herzallah, Mohammad M, Gluck, Mark A, Sharp, Trevor, Harmer, Catherine J, Vasudevan, Sridhar R, Cowen, Philip J, Churchill, Grant C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770517/
https://ncbi.nlm.nih.gov/pubmed/26593266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.343
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