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A randomized double-blind, placebo-, and active-controlled study of T-type calcium channel blocker ABT-639 in patients with diabetic peripheral neuropathic pain
T-type Ca(v)3.2 calcium channels represent a novel target for neuropathic pain modulation. Preclinical studies with ABT-639, a peripherally acting highly selective T-type Ca(v)3.2 calcium channel blocker, showed dose-dependent reduction of pain in multiple pain models. ABT-639 also demonstrated an a...
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Publicado no: | Pain |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Wolters Kluwer
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4770341/ https://ncbi.nlm.nih.gov/pubmed/26067585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000263 |
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