Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients

OBJECTIVE: Epigenetic modifications contribute to the etiology of type 2 diabetes. METHOD: We performed genome-wide methylome and transcriptome analysis in liver from severely obese men with or without type 2 diabetes and non-obese men to discover aberrant pathways underlying the development of insu...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kirchner, Henriette, Sinha, Indranil, Gao, Hui, Ruby, Maxwell A., Schönke, Milena, Lindvall, Jessica M., Barrès, Romain, Krook, Anna, Näslund, Erik, Dahlman-Wright, Karin, Zierath, Juleen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770265/
https://ncbi.nlm.nih.gov/pubmed/26977391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.12.004
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