Automated design of hammerhead ribozymes and validation by targeting the PABPN1 gene transcript

We present a new publicly accessible web-service, RiboSoft, which implements a comprehensive hammerhead ribozyme design procedure. It accepts as input a target sequence (and some design parameters) then generates a set of ranked hammerhead ribozymes, which target the input sequence. This paper descr...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Kharma, Nawwaf, Varin, Luc, Abu-Baker, Aida, Ouellet, Jonathan, Najeh, Sabrine, Ehdaeivand, Mohammad-Reza, Belmonte, Gabriel, Ambri, Anas, Rouleau, Guy, Perreault, Jonathan
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Methods Online
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770207/
https://ncbi.nlm.nih.gov/pubmed/26527730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1111
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