Live imaging of osteoclast inhibition by bisphosphonates in a medaka osteoporosis model

Osteoclasts are bone-resorbing cells derived from the monocyte/macrophage lineage. Excess osteoclast activity leads to reduced bone mineral density, a hallmark of diseases such as osteoporosis. Processes that regulate osteoclast activity are therefore targeted in current osteoporosis therapies. To i...

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Bibliographic Details
Published in:Dis Model Mech
Main Authors: Yu, Tingsheng, Witten, Paul Eckhard, Huysseune, Ann, Buettner, Anita, To, Thuy Thanh, Winkler, Christoph
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770141/
https://ncbi.nlm.nih.gov/pubmed/26704995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019091
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