Mitochondrial calcium uniporter inhibition attenuates mouse bone marrow-derived mast cell degranulation induced by beta-1,3-glucan

Mast cells are primary mediators of allergic inflammation. Beta-1,3-glucan (BG) protects against infection and shock by activating immune cells. Activation of the BG receptor induces an increase in intracellular Ca(2+), which may induce exocytosis. However, little is known about the precise mechanis...

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Publicat a:Korean J Physiol Pharmacol
Autors principals: Cuong, Dang Van, Kim, Hyoung Kyu, Marquez, Jubert, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin
Format: Artigo
Idioma:Inglês
Publicat: The Korean Physiological Society and The Korean Society of Pharmacology 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770112/
https://ncbi.nlm.nih.gov/pubmed/26937218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2016.20.2.213
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