The Val66Met Brain-Derived Neurotrophic Factor Gene Variant Interacts with Early Pain Exposure to Predict Cortisol Dysregulation in 7-year-old Children Born Very Preterm: Implications for Cognition

Early stress in the form of repetitive neonatal pain, in infants born very preterm, is associated with long-term dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and with poorer cognitive performance. Brain-derived neurotrophic factor (BDNF) which is important in synaptic plasticity an...

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Détails bibliographiques
Publié dans:Neuroscience
Auteurs principaux: Chau, Cecil MY, Cepeda, Ivan L, Devlin, Angela M., Weinberg, Joanne, Grunau, Ruth E
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769966/
https://ncbi.nlm.nih.gov/pubmed/26318333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.08.044
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