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Eosinophil Resistance to Glucocorticoid-Induced Apoptosis is Mediated by the Transcription Factor NFIL3

The mainstay of asthma therapy, glucocorticoids (GCs) exert their therapeutic effects through the inhibition of inflammatory signaling and induction of eosinophil apoptosis. However, laboratory and clinical observations of GC-resistant asthma suggest that GCs' effects on eosinophil viability ma...

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Publicat a:Apoptosis
Autors principals: Pazdrak, Konrad, Moon, Young, Straub, Christof, Stafford, Susan, Kurosky, Alexander
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769953/
https://ncbi.nlm.nih.gov/pubmed/26880402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-016-1226-5
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