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SARM1, not MyD88, mediates TLR7/TLR9-induced apoptosis in neurons()

Neuronal apoptosis is a key aspect of many different neurological diseases, but the mechanisms remain unresolved. Recent studies have suggested a mechanism of innate immune-induced neuronal apoptosis that may act through the stimulation of toll-like receptors (TLR) in neurons. TLRs are stimulated bo...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Mukherjee, Piyali, Winkler, Clayton W., Taylor, Katherine G., Woods, Tyson A., Nair, Vinod, Khan, Burhan A., Peterson, Karin E.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769638/
https://ncbi.nlm.nih.gov/pubmed/26423149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500953
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