Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits

BACKGROUND: Dense SNP genotypes are often combined with complex trait phenotypes to map causal variants, study genetic architecture and provide genomic predictions for individuals with genotypes but no phenotype. A single method of analysis that jointly fits all genotypes in a Bayesian mixture model...

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Bibliografski detalji
Izdano u:BMC Genomics
Glavni autori: MacLeod, I. M., Bowman, P. J., Vander Jagt, C. J., Haile-Mariam, M., Kemper, K. E., Chamberlain, A. J., Schrooten, C., Hayes, B. J., Goddard, M. E.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Methodology Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769584/
https://ncbi.nlm.nih.gov/pubmed/26920147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2443-6
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