Celastrol protects mouse retinas from bright light-induced degeneration through inhibition of oxidative stress and inflammation

BACKGROUND: Photoreceptor death leads to vision impairment in several retinal degenerative disorders. Therapies protecting photoreceptor from degeneration remain to be developed. Anti-inflammation, anti-oxidative stress, and neuroprotective effects of celastrol have been demonstrated in a variety of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Neuroinflammation
Main Authors: Bian, Minjuan, Du, Xiaoye, Cui, Jingang, Wang, Peiwei, Wang, Wenjian, Zhu, Weiliang, Zhang, Teng, Chen, Yu
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769581/
https://ncbi.nlm.nih.gov/pubmed/26920853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0516-8
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