Production of the forskolin precursor 11β-hydroxy-manoyl oxide in yeast using surrogate enzymatic activities

BACKGROUND: Several plant diterpenes have important biological properties. Among them, forskolin is a complex labdane-type diterpene whose biological activity stems from its ability to activate adenylyl cyclase and to elevate intracellular cAMP levels. As such, it is used in the control of blood pre...

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Dettagli Bibliografici
Pubblicato in:Microb Cell Fact
Autori principali: Ignea, Codruta, Ioannou, Efstathia, Georgantea, Panagiota, Trikka, Fotini A., Athanasakoglou, Anastasia, Loupassaki, Sofia, Roussis, Vassilios, Makris, Antonios M., Kampranis, Sotirios C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769550/
https://ncbi.nlm.nih.gov/pubmed/26920948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0440-8
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