Fluid-induced, shear stress-regulated extracellular matrix and matrix metalloproteinase genes expression on human annulus fibrosus cells

BACKGROUND: Mechanical loading plays an important role in the regulation of extracellular matrix (ECM) homeostasis as well as pathogenesis of intervertebral disc (IVD) degeneration. The human annulus fibrosus (hAF) in the IVD is subjected to contact shear stress during body motion. However, the effe...

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Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Chou, Po-Hsin, Wang, Shih-Tien, Yen, Meng-Hua, Liu, Chien-Lin, Chang, Ming-Chau, Lee, Oscar Kuang-Sheng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769486/
https://ncbi.nlm.nih.gov/pubmed/26921206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0292-5
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