CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis

γδ T cells can either enhance or inhibit an adaptive immune response, but the mechanisms involved are not fully understood. Given that CD73 is the main enzyme responsible for conversion of AMP into the immunosuppressive molecule adenosine, we investigated its role in the regulatory function of γδ T...

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Publicat a:PLoS One
Autors principals: Liang, Dongchun, Zuo, Aijun, Zhao, Ronglan, Shao, Hui, Born, Willi K., O'Brien, Rebecca L., Kaplan, Henry J., Sun, Deming
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769068/
https://ncbi.nlm.nih.gov/pubmed/26919582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150078
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