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Knockout of phospholipase Cε attenuates N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder tumorigenesis

Bladder cancer frequently shows mutational activation of the oncogene Ras, which is associated with bladder carcinogenesis. However, the signaling pathway downstream of Ras remains to be fully elucidated. N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) is able to induce bladder cancer by driving the cl...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: JIANG, TAIMAO, LIU, TAO, LI, LIN, YANG, ZHIJUN, BAI, YUNFENG, LIU, DONGYE, KONG, CHUIZE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768990/
https://ncbi.nlm.nih.gov/pubmed/26782701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2016.4762
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