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Validation of Methotrexate-First Strategy in Patients with Early, Poor-Prognosis Rheumatoid Arthritis: Results From a Two-Year Randomized, Double-Blind Trial

OBJECTIVE: Methotrexate (MTX) taken as monotherapy is recommended as the initial disease-modifying antirheumatic drug for rheumatoid arthritis (RA). The purpose of this study was to examine outcomes of a blinded trial of initial MTX monotherapy with the option to step-up to combination therapy as co...

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Detalhes bibliográficos
Publicado no:Arthritis Rheum
Main Authors: O'Dell, James R., Curtis, Jeffrey R., Mikuls, Ted R., Cofield, Stacey S., Bridges, S. Louis, Ranganath, Veena K., Moreland, Larry
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768726/
https://ncbi.nlm.nih.gov/pubmed/23686414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38012
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