Structural and Enzymatic Characterization of ABgp46, a Novel Phage Endolysin with Broad Anti-Gram-Negative Bacterial Activity

The present study demonstrates the antibacterial potential of a phage endolysin against Gram-negative pathogens, particularly against multidrug resistant strains of Acinetobacter baumannii. We have cloned, heterologously expressed and characterized a novel endolysin (ABgp46) from Acinetobacter phage...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Oliveira, Hugo, Vilas Boas, Diana, Mesnage, Stéphane, Kluskens, Leon D., Lavigne, Rob, Sillankorva, Sanna, Secundo, Francesco, Azeredo, Joana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768612/
https://ncbi.nlm.nih.gov/pubmed/26955368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.00208
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