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NNMT: A Bad Actor in Fat Makes Good in Liver
High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methylnicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high fat diet, Hong et al. now show that high hepatic expression of NNMT improves lipid parameters via SIRT1...
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| Gepubliceerd in: | Cell Metab |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4768475/ https://ncbi.nlm.nih.gov/pubmed/26244929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.07.017 |
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