Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

We studied the safety and clinical outcomes of patients treated with umbilical cord blood (UCB)-derived regulatory T cells (Tregs) that expanded in cultures stimulated with K562 cells modified to express the high-affinity Fc receptor (CD64) and CD86, the natural ligand of CD28 (KT64/86). Eleven pati...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Blood
Hlavní autoři: Brunstein, Claudio G., Miller, Jeffrey S., McKenna, David H., Hippen, Keli L., DeFor, Todd E., Sumstad, Darin, Curtsinger, Julie, Verneris, Michael R., MacMillan, Margaret L., Levine, Bruce L., Riley, James L., June, Carl H., Le, Chap, Weisdorf, Daniel J., McGlave, Philip B., Blazar, Bruce R., Wagner, John E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768428/
https://ncbi.nlm.nih.gov/pubmed/26563133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-653667
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky