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Cigarette Smoking and Gemcitabine-Induced Neutropenia in Advanced Solid Tumors

BACKGROUND: Chemotherapy-associated neutropenia has been reported to be a pharmacodynamic marker of response in some advanced solid tumors. Factors that accelerate drug clearance lead to lower plasma concentrations and toxicity, including neutropenia. Smoking accelerates themetabolism of several dru...

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Библиографические подробности
Опубликовано в: :Oncology
Главные авторы: O’Malley, Meaghan, Healy, Patrick, Daignault, Stephanie, Ramnath, Nithya
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768297/
https://ncbi.nlm.nih.gov/pubmed/24080957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000355107
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