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A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate

Three important physical properties which may affect the performance of glycoconjugate vaccines against serious disease are molar mass (molecular weight), heterogeneity (polydispersity), and conformational flexibility in solution. The dilute solution behaviour of native and activated capsular polyri...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abdelhameed, Ali Saber, Adams, Gary G., Morris, Gordon A., Almutairi, Fahad M., Duvivier, Pierre, Conrath, Karel, Harding, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768162/
https://ncbi.nlm.nih.gov/pubmed/26915577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22208
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