Asialoglycoprotein receptor-magnetic dual targeting nanoparticles for delivery of RASSF1A to hepatocellular carcinoma

We developed a nanovector with double targeting properties for efficiently delivering the tumor suppressor gene RASSF1A specifically into hepatocellular carcinoma (HCC) cells by preparing galactosylated-carboxymethyl chitosan-magnetic iron oxide nanoparticles (Gal-CMCS-Fe(3)O(4)-NPs). After conjugat...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Xue, Wan-Jiang, Feng, Ying, Wang, Fei, Guo, Yi-Bing, Li, Peng, Wang, Lei, Liu, Yi-Fei, Wang, Zhi-Wei, Yang, Yu-Min, Mao, Qin-Sheng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768135/
https://ncbi.nlm.nih.gov/pubmed/26915683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22149
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