VTX‐1463, a novel TLR‐8 agonist, attenuates nasal congestion after ragweed challenge in sensitized beagle dogs

VTX‐1463 is a selective toll‐like receptor (TLR) 8 agonist that activates a subset of innate immune cells to produce a unique cytokine profile. Delivery of VTX‐1463 via nasal spray may modulate the nasal response in allergic rhinitis. The aim of this study was to determine the effects of VTX‐1463 on...

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Bibliographic Details
Published in:Immun Inflamm Dis
Main Authors: Royer, Christopher M., Rudolph, Karin, Dietsch, Gregory N., Hershberg, Robert M., Barrett, Edward G.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4768068/
https://ncbi.nlm.nih.gov/pubmed/27042301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.91
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