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Effects of Fostamatinib on the Pharmacokinetics of Oral Contraceptive, Warfarin, and the Statins Rosuvastatin and Simvastatin: Results From Phase I Clinical Studies

BACKGROUND AND OBJECTIVES: Fostamatinib is a spleen tyrosine kinase inhibitor that has been investigated as therapy for rheumatoid arthritis and immune thrombocytopenic purpura. The present studies assessed the potential for pharmacokinetic interaction between fostamatinib and the commonly prescribe...

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Detalhes bibliográficos
Publicado no:Drugs R D
Main Authors: Martin, P., Gillen, M., Ritter, J., Mathews, D., Brealey, C., Surry, D., Oliver, S., Holmes, V., Severin, P., Elsby, R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767723/
https://ncbi.nlm.nih.gov/pubmed/26748647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-015-0120-x
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