Apolipoprotein A-IV inhibits AgRP/NPY neurons and activates POMC neurons in the arcuate nucleus

BACKGROUND/AIMS: Apolipoprotein A-IV (apoA-IV) in the brain potently suppresses food intake. However the mechanisms underlying its anorexigenic effects remain to be identified. METHODS: We first examined the effects of apoA-IV on cellular activities in hypothalamic neurons that co-express agouti-rel...

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Veröffentlicht in:Neuroendocrinology
Hauptverfasser: Yan, Chunling, He, Yanlin, Xu, Yuanzhong, Shu, Gang, Wang, Chunmei, Yang, Yongjie, Saito, Kenji, Xu, Pingwen, Hinton, Antentor Othrell, Yan, Xiaofeng, Yu, Likai, Wu, Qi, Tso, Patrick, Tong, Qingchun, Xu, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767704/
https://ncbi.nlm.nih.gov/pubmed/26337236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000439436
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