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Integrative studies of scleroderma-associated genetic and environmental factors with fibroblasts identify polymorphisms of TNFAIP3 in association with MMP expression
OBJECTIVES: Systemic Sclerosis (SSc) is a fibrotic disease attributed to both genetic susceptibility and environmental factors. Our studies tried to demonstrate how human fibroblasts with SSc associated genetic variants respond to time-course and dose-response expression of the extracellular matrix...
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| Publicado en: | Arthritis Rheumatol |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767670/ https://ncbi.nlm.nih.gov/pubmed/26474180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39476 |
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