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Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of Polycomb Group proteins
The Drosophila Piwi protein regulates both niche and intrinsic mechanisms to maintain germline stem cells, but its underlying mechanism remains unclear. Here we report that Piwi cooperates with Polycomb Group complexes PRC1 and PRC2 in niche and germline cells to regulate ovarian germline stem cells...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4767590/ https://ncbi.nlm.nih.gov/pubmed/26780607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3486 |
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